Lid scrubbing with a gel combining natural extracts for dry eye treatment

Evaluation of treatment for dry eye with 2-hydroxyestradiol using a dry eye rat model

PURPOSE 2-hydroxy estradiol (2-OHE2) is a catechol derivative of 17β -Estradiol (E2) and it is synthesized from E2 catalyzed by cytochrome P4501A1. Previous studies reported that 2-OHE2 is a physiologic antioxidant in lipoproteins, liver microsomes, and the brain. Catechol derivatives show an anti-inflammatory effect through the inhibition of prostaglandin endoperoxide synthase (PGS) activity. ...

Eye shield with removable lid.

The prime cause of corneal damage in exposure keratitis is desiccation. This results from failure of the lids to cover the cornea for either mechanical or neurological reasons. In such cases the application of a closely-fitting shield affords considerable protection because a pocket of humid air is trapped in front of the cornea. Several simple occlusive shields have been described utilizing su...

Incomplete blinking: exposure keratopathy, lid wiper epitheliopathy, dry eye, refractive surgery, and dry contact lenses.

Exposure keratopathy, including that which occurs following laser assisted keratomileusis, appears to be associated with incomplete blinking. Incomplete blinking may contribute to the signs and symptoms of lid wiper epitheliopathy. In addition, precipitation of contact lens surface deposits and other contact lens surface drying phenomena, appear to be accelerated by incomplete blinking. For the...

[New formulations for dry eye treatment].

Lid-parallel conjunctival folds (LIPCOF) and dry eye: a multicentre study.

AIMS The study was designed to test the clinical application of the grading of lid-parallel conjunctival folds (LIPCOF) as a diagnostic test for dry eye. METHODS At 12 centres in 11 countries, 272 eyes of 272 dry eye patients (75 men, 197 women) were examined. Their mean age was 52.7±16.2 years. The LIPCOF were graded according to the method of Höh et al. The tear film break-up time (BUT) was...